Brief overviews of the top rural health concerns and objectives associated with Healthy People 2010 focus areas, including, Access to Quality Health Services (Insurance, Primary Care, and EMS); Cancer; Diabetes; Heart Disease and Stroke; Maternal, Infant, and Child Health; Mental Health and Mental Disorders; Nutrition and Overweight Concerns; Oral Health; Substance Abuse; and Tobacco Use. Also included are references to key literature about these concerns, and descriptions of models for practice that rural communities can draw upon to achieve key Healthy People 2010 objectives.